SINCE 20005


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Fabrizio Rossi, Camille Stephan-Otto Attolini, Jose Luis Mosquera, Cayetano Gonzalez (2017). Drosophila larval brain neoplasms present tumour-type dependent genome instability. BioRxiv. doi:

Rossi F, Molnar C, Hashiyama K, Heinen JP, Pampalona J, Llamazares S, Reina J, Hashiyama T, Rai M, Pollarolo G, Fernández-Hernández I, Gonzalez C. (2016). An in vivo genetic screen in Drosophila identifies the orthologue of human cancer/testis gene SPO11 among a network of targets to inhibit lethal(3)malignant brain tumour growth. Open Biology 2017 Aug;7(8). pii: 170156. doi: 10.1098/rsob.170156.

Chen K, Koe CT, Xing ZB, Tian X, Rossi F, Wang C, Tang Q, Zong W, Hong WJ, Taneja R, Yu F, Gonzalez C, Wu C, Endow S, Wang H (2016). Arl2- and Msps-dependent microtubule growth governs asymmetric division. Journal of Cell Biology  212:661-76. doi: 10.1083/jcb.201503047. 

Zhang Y, Rai M, Wang C, Gonzalez C, and Wang H (2016). Prefoldin and Pins synergistically regulate asymmetric division and suppress dedifferentiation. Scientific Reports. Mar 30;6:23735. doi: 10.1038/srep23735.

Gonzalez C (2015). Cell division: A last-minute decision. Nature N&V 528: 196-197. doi:10.1038/528196a.

Rossi F. and Gonzalez C. (2015). Studying tumor growth in Drosophila using the tissue allograft method.Nature Protocols.Oct;10(10):1525-34. doi: 10.1038/nprot.2015.096. Epub 2015 Sep 10.

Gottardo M, Pollarolo G, Llamazares S, Reina J, Riparbelli MG, Callaini G, Gonzalez C. (2015). Loss of Centrobin Enables Daughter Centrioles to Form Sensory Cilia in Drosophila. Current Biology.Aug 19. pii: S0960-9822(15)00872-6. doi: 10.1016/j.cub.2015.07.038. [Epub ahead of print].

Pampalona, J., Januschke, J., Sampaio, P. & Gonzalez, C. (2015). Time-lapse recording of centrosomes and other organelles in Drosophila neuroblasts in Methods in cell biology. Centrosome & Centriole (Academic Press). vol 129 Chapter 16 pp301-316. Edited by Renata Basto & Karen Oegema.

Pollarolo, G. and Gonzalez, C (2014).Quantitative differences, qualitative outcomes.Elife. 2014 Oct 29;3. doi: 10.7554/eLife.04869.

Reina, J, and Gonzalez, C. (2014). When fate follows age: unequal centrosomes in asymmetric cell division. Phil. Trans. R. Soc. B. 2014 369 1650 20130466; doi:10.1098/rstb.2013.0466 (published 21 July 2014) 1471-2970

Koe CT, Li S, Rossi F, Wong JJ, Wang Y, Zhang Z, Chen K, Aw SS, Richardson HE, Robson P, Sung WK, Yu F, Gonzalez C, Wang H. (2014) The Brm-HDAC3-Erm repressor complex suppresses dedifferentiation in Drosophila type II neuroblast lineages. Elife. DOI: 10.7554/eLife.01906.001

Rebollo E, and Gonzalez C (2013). Time-lapse imaging of embryonic neural stem cell division in Drosophila by two-photon microscopy.Current Protocols Select: Imaging and Microscopy, 561-570. Edited by S.C. Watkins & C.M. St Croix. J. Wiley and sons. ISBN 978-1-118-04431-5 (pbk.) Originally: Rebollo E, and Gonzalez C (2010) Current Protocols in Stem Cell Biology 13:1H.2.1-1H.2.9

Gonzalez, C. (2013). Drosophila melanogaster: a model and a tool to investigate malignancy and identify new therapeutics. Nature Reviews Cancer | doi:10.1038/nrc3461.

Januschke, J.. Reina,J., Llamazares, S., Bertran, T., Rossi, F., Roig, J.,& Gonzalez, C. (2013).Centrobin controls mother-daughter centriole asymmetry in Drosophila neuroblasts. Nature Cell Biology doi:10.1038/ncb2671.

Mapelli, M. and Gonzalez, C. (2012).On the inscrutable role of Inscuteable: structural basis and functional implications for the competitive binding of NuMA and Inscuteable to LGN.Open Biology Royal Society 2:120102.

Delgehyr N, Wieland U, Rangone H, Pinson X, Mao G, Dzhindzhev NS, McLean D, Riparbelli MG, Llamazares S,Callaini G, Gonzalez C, Glover DM (2012) Drosophila Mgr, a Prefoldin subunit cooperating with von Hippel Lindau to regulate tubulin stability. Proc Natl Acad Sci U S A. Mar 26. [Epub ahead of print]

Haupt A, Joberty G, Bantscheff M, Frohlich H, Stehr H, Schweiger MR, Fischer A, Kerick M, Boerno ST, Dahl A, Lappe M, Lehrach H, Gonzalez C, Drewes G, Lange BM. (2012).Hsp90 inhibition differentially destabilises MAP kinase and TGF-beta signalling components in cancer cells revealed by kinase-targeted chemoproteomics. BMC Cancer. 2012 Jan 25;12(1):38. [Epub ahead of print]

Rossi F, Gonzalez C. (2012).Synergism between altered cortical polarity and the PI3K/TOR pathway in the suppression of tumour growth.EMBO Rep.13:157-62. doi: 10.1038/embor.2011.230.

Wang C, Li S, Januschke J, Rossi F, Izumi Y, Garcia-Alvarez G, Gwee SS, Soon SB, Sidhu HK, Yu F, Matsuzaki F, Gonzalez C, Wang H. (2011).An ana2/ctp/mud complex regulates spindle orientation in Drosophila neuroblasts. Dev. Cell 21:520-33. doi 10.1016/j.devcel.2011.08.002

Januschke, J., Llamazares, S., Reina, J., and Gonzalez, C. (2011). Drosophila neuroblasts retain the daughter centrosome. Nature Communications. 2:243

Janic, A., Mendizabal, L., Llamazares, S., Rossell, D. & Gonzalez, C. (2010). Ectopic Expression of Germline Genes Drives Malignant Brain Tumor Growth in Drosophila. Science. 330:1824-1827

Chang, KC., Garcia-Alvarez, G., Somers, G., Sousa-Nunes, R., Rossi, F., Lee, Y. Y., Soon, SB, Gonzalez, C., Chia, W. & Wang, H. (2010). Interplay between the Transcription Factor Zif and aPKC Regulates Neuroblast Polarity and Self-Renewal. Dev. Cell. 19: 778-785.

Lesage, B., Gutierrez, I., Marti, E. & Gonzalez, C. (2010). Neural stem cells: the need for a proper orientation. Curr. Op. in Genetics & Development. 20:438-442. Review.

Januschke, J. & Gonzalez, C. (2010). The interphase microtubule aster is a determinant of asymmetric division orientation in Drosophila neuroblasts. J Cell Biol. 188:693-706.

Tajbakhsh, S. & Gonzalez, C. (2009). Biased segregation of DNA and centrosomes- moving together or drifting apart? Nature Reviews Molecular Cell Biology 10: 804-810. Review.

Rebollo E, Roldan M & Gonzalez C. (2009). Spindle alignment is achieved without rotation after the first cell cycle in Drosophila embryonic neuroblasts.Development. 136: 3393-97.

Martinez AM , Schuettengruber B, Sakr S, Janic A., Gonzalez C. & Cavalli G. (2009). Polyhomeotic has a tumor suppressor activity mediated by repression of Notch signaling. Nature Genetics. 41:1076-82.

Januschke J. & Gonzalez C. (2008) Drosophila asymmetric division, polarity and cancer. Oncogene. 27(55), 6994-7002.Review.

Castellanos E., Dominguez P. & Gonzalez C. (2008) Centrosome dysfunction in Drosophila neural stem cells causes tumours that are not due to genome instability. Current Biol. 18(16):1209-14.

Gonzalez C. (2008) Centrosome function during stem cell division: The devil is in the details. Curr. Op. Cell Biol. 6: 694-698.Review.

Dyer N, E Rebollo, P Dominguez, N Elkhatib, P Chavrier, L Daviet, C Gonzalez, and M Gonzalez-Gaitan. (2007). Spermatocyte cytokinesis requires rapid membrane addition mediated by ARF6 on central spindle recycling endosomes. Development. 134(24), 4437-47.

Varmark, H., Llamazares, S., Rebollo, E., Lange, B., Reina, J., Schwarz, H., Gonzalez, C. (2007). Asterless is a constitutive centriolar protein required to organize functional centrosomes and essential to trigger zygotic development in Drosophila. Curr Biol. 17(20):1735-45.

Gonzalez C (2007) Spindle orientation, asymmetric division and tumour suppression in Drosophila stem cells. Nature Reviews Genetics 8, 462-472. Review.

Rebollo E., Sampaio P., Januschke J., Varmark H., Llamazares S., and Gonzalez C. (2007) Functionally Unequal Centrosomes Drive Spindle Orientation in Asymmetrically Dividing Drosophila Neural Stem Cells. Dev.Cell, 2007 Mar;12(3):467-474.

Wodarz A and C. Gonzalez (2006) Connecting Cancer to the Asymmetric Division of Stem Cells. Cell, 124 (6): 1121-1123. Review.

Santori,MI C. Gonzalez, L. Serrano and M. Isalan (2006) Localized transfection with magnetic beads coated with PCR products and other nucleic acids. Nature Protocols 1, 526 – 531.

Caussinus, E. and González, C. (2005) Induction of tumor growth by altered stem cell division in Drosophila. Nat Genet. 37(10):1125-9.

Lange, B.M.H., Kirfel, G., Gestmann, I., Herzog, V. and, González, C. (2005). Structure and Microtubule-Nucleation Activity of Isolated Drosophila Embryo Centrosomes Characterized by Whole Mount Scanning and Transmission Electron Microscopy. Histochemistry and Cell Biology. 124 (3-4): 325 -334

Isalan, M., Santori, M.I., Gonzalez, C. and Serrano, L. (2005) Localized transfection on PCR-coated magnetic arrays. Nat. Methods. 2: 113-118.


(C) Gonzalez 2015